Actos, and a similar drug marketed as Avandia, have come under serious scrutiny by the FDA, health experts, and consumer advocates because of the significantly increased risk of heart-related side effects.
Cardiovascular side effects are of serious concern among diabetic patients because the disease itself increases the risk of cardiovascular complications. In fact, an estimated 65 percent of all Type-2 diabetes related deaths are the result of heart related complications.
Other Actos Side EffectsClinical evidence shows that Actos significantly increases the risk of bone fracture, particularly fractures of the distal upper and lower limbs, in female patients. While the mechanism responsible for increased risk of Actos bone fracture is unknown, patients with an increased risk of bone fracture should weigh this side effect risk with potential benefits when considering treatment with Actos.